She continued to improve her profession in the judge of the Yerevan State Pantomime Theater (2003), in the director's laboratories of Anatoly Vasilyev (Moscow, 2005) and Lev Dodin (St. Petersburg, 2007), participated in the laboratories of the Chekhov International Theater Festival (2004). She took a course in theater management in Boston and a course in theater directing at the Grotowski Institute in Wroclaw.
She has played more than thirty theater and cinema roles. She has worked as a director at the Yerevan State Puppet Theater named after O. Tumanyan, the State Russian Drama Theater named after K. Stanislavsky, the State Pantomime Theater, and the State Theater "Amazgain" named after Sos Sargsyan. Since 2009, he has been teaching at the Yerevan State Institute of Theater and Cinema, Associate Professor of GITiK. Since 2019 — Artistic director of the State Theater "Amazgain" named after Sos Sargsyan.
Multiple winner of the National Theater Award "Artavazd" in the categories "best actress" and "best director". Narine Grigoryan's performances have participated in many international theater festivals, including "Golden Mask", "Mask+" program (Moscow), "Meetings in Russia" (St. Petersburg), Youth Theater Forum — the 2nd prize of the festival for the performance Flight over the City, which was also awarded the Grand Prix of the International Festival "March-contact" in Mogilev (Belarus). Narine Grigoryan's autobiographical solo performance My Family in My Suitcase won the Grand Prix of the Aspindis International Solo Performance Festival (Lithuania, 2017). In 2020, Narine Grigoryan won twice in the category "best actress" — at the International Festival "Kinoshok" in Anapa and the International Film Festival in Rome — for the main role in the film of the Iranian director Anahit Abad Eva .
Narine Grigoryan's last two works as a director — the plays Loretsi Sako and Boule de suif — were awarded the national theater award "Artavazd" in five categories, and the play Boule de suif was also declared "the best performance of 2020".